Sinonasal Adenocarcinoma: Update on Classification, Immunophenotype and Molecular Features

Sinonasal Adenocarcinoma: Update on Classification, Immunophenotype and Molecular Features.

Adenocarcinomas of the sinonasal tract may originate from respiratory surface epithelium or the underlying seromucinous glands. These malignancies are divided into salivary-type adenocarcinomas and non-salivary-type adenocarcinomas. The latter are further divided into intestinal-type and nonintestinal-type adenocarcinomas. This review provides an update on tumor classification, differential dia...

Intestinal-Type Adenocarcinoma: Classification, Immunophenotype, Molecular Features and Differential Diagnosis

Intestinal-type adenocarcinoma is the second most frequent sinonasal adenocarcinoma. High incidence of these tumors is seen among workers with occupational wood dust exposure, particularly of hardwood dusts. Intestinal-type adenocarcinoma has striking histomorphologic and immunophenotypic similarities with colorectal adenocarcinomas, but on the level of molecular pathologic mechanisms these tum...

Sinonasal lymphomas in Indonesia: immunophenotype and Epstein-Barr virus association

Sinonasal lymphoma is a rare disease with NK/T-cell (NKTC) or B-cell immunophenotype. Previous study revealed the geographic difference in frequency of NKTC lymphoma (NKTCL) and almost constant association with Epstein-Barr virus (EBV) infection. Through review of 41 cases with sinonasal lymphoproliferative diseases registered in the Department of Anatomical Pathology, University of Indonesia d...

Molecular Features and Their Clinical Implications on Gastric Adenocarcinoma

Update on Plant Lipoxygenases Plant Lipoxygenases. Physiological and Molecular Features

Lipoxygenases (LOXs; EC 1.13.11.12) are nonheme iron-containing dioxygenases widely distributed in plants and animals. LOX catalyzes the addition of molecular oxygen to polyunsaturated fatty acids containing a (Z,Z)-1,4-pentadiene system to produce an unsaturated fatty acid hydroperoxide. LOX initiates the synthesis of a group of acyclic or cyclic compounds collectively called oxylipins, which ...